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Hi _m, Thanks for your reply. Your slution works if both x and 2 are unique. I should be more specific in posing the question What I am trying to do is actually to search through a large text file, to find a particular substring say nrel=0, and change it to nrel=1. In this case, 0 is not unique, but...

Hi Toshiro,
I tried this and it seemed to work for a tilde.
Doesn't work for me when its an equal sign

set str=simple equation yahoo~com
echo.%str%
set str=%str:o~c=o.c%
echo.%str%

Under the section Replace a substring using string substitution, an example is given as set str=teh cat in teh hat echo.%str% set str=%str:teh=the% echo.%str% what if the substring to be replaced contains an equal sign? For instance. try replace x=2 by y=3 set str=simple equation x=2 echo.%str% set ...